Biology of Business

NASDAQ 100

67 companies

Apple

Consumer Electronics / Technology

Apple defied every Silicon Valley orthodoxy - and captured 80% of smartphone industry profits with 25% market share. The lesson: boundaries aren't bar...

15 mentions sp500, nasdaq100

Netflix

Entertainment / Streaming

Netflix has died and been reborn three times - DVD rental (1997-2007), streaming service (2007-2013), global content studio (2013-present). Most compa...

15 mentions sp500, nasdaq100

Amazon

E-commerce & Cloud Computing

Amazon mastered what kills most companies: strategic reallocation across time horizons. From 1997-2000, Jeff Bezos executed the Pacific Salmon strateg...

14 mentions sp500, nasdaq100

Microsoft

Software & Cloud Computing

Microsoft's transformation under Satya Nadella represents one of the most successful metabolic pathway shifts in business history. By 2014, the compan...

9 mentions sp500, nasdaq100

Airbnb

Travel & Hospitality Technology

Airbnb's origin story reads like a case study in biological stress response. In September 2008, three founders had $5,000 in the bank, $20,000 in cred...

8 mentions nasdaq100

Intel

Semiconductor Manufacturing

Intel created the x86 architecture in 1978 and spent four decades running the Red Queen's race - investing $15-20 billion annually in R&D just to main...

6 mentions sp500, nasdaq100

Taiwan Semiconductor (TSMC)

Semiconductor Manufacturing

TSMC didn't invent semiconductors - it invented trust at scale. When Morris Chang proposed a pure-play foundry in 1987, every major chip company rejec...

4 mentions nasdaq100

Shopify

E-commerce Platform & Technology

Shopify started when Tobias Lütke wanted to sell snowboards online and found every platform inadequate. So he built his own - then realized the infras...

3 mentions nasdaq100

Alphabet (Google)

Technology / Holding Company

Alphabet's 2015 restructuring promised moonshots at scale—autonomous vehicles, longevity research, delivery drones. Google would become a holding comp...

2 mentions sp500, nasdaq100

ASML Holding

Semiconductor Equipment

ASML holds a 100% monopoly on the machines that make modern computing possible - and impossibly expensive. The Dutch company's extreme ultraviolet (EU...

2 mentions nasdaq100

Bombardier

Aerospace

Canadian aerospace company that developed the C Series aircraft program before selling it to Airbus in 2018 for effectively zero dollars. The Bombardi...

2 mentions nasdaq100

Starbucks

Coffee Retail

Starbucks' Australian failure represents the definitive case study of the Phenotype Fallacy - copying the visible expression of success without unders...

2 mentions sp500, nasdaq100

Texas Instruments

Semiconductors

Texas Instruments made a decade-long bet on 300mm wafer manufacturing when competitors hesitated, investing $5-7 billion annually in fab capacity. The...

2 mentions sp500, nasdaq100

Zoom

Video Communications / SaaS

Eric Yuan founded Zoom in 2011 after leaving Cisco WebEx, detecting signals others missed: terrible video quality, desktop-first products in a mobile-...

2 mentions nasdaq100

Coinbase

Cryptocurrency

Coinbase doubled revenue to $6.6 billion in 2024 while transforming from pure transaction exchange to diversified infrastructure platform—a textbook c...

1 mention nasdaq100

Costco

Retail / Warehouse Club

Costco disrupted retail not with technology or logistics, but with a $60 membership fee. When the company launched in 1983, conventional wisdom said t...

1 mention sp500, nasdaq100

DoorDash

Food Delivery

DoorDash processed $80 billion in gross order value across 2.6 billion orders in 2024, generating $10.72 billion in revenue (up 24.2%) and its first a...

1 mention nasdaq100

Intuit

Financial Software

Financial software company known for its innovative approach to failure through 'failure parties.' When a project is killed, the team throws a party t...

1 mention sp500, nasdaq100

Nvidia Corporation

Semiconductors / AI Hardware

Nvidia briefly touched $4 trillion market capitalization in July 2025—the first company ever to reach this threshold—before settling at $4.4 trillion...

1 mention sp500, nasdaq100

PayPal

Financial Technology / Payments

PayPal's story is about strategic focus under pressure. During the 2000 dot-com crash, the company demonstrated what biologists call 'shivering thermo...

1 mention nasdaq100

Tesla

Automotive / Electric Vehicles

Tesla went all-in on battery electric vehicles in 2008 when every other automaker was hedging. That single strategic bet—choosing speed over optionali...

1 mention sp500, nasdaq100

Unilever

Consumer Goods & FMCG

Unilever generated €60.8 billion revenue in 2024 ($65.7B USD), up 1.9% with 4.2% underlying sales growth driven by 2.9% volume increases across Person...

1 mention ftse100, sp500 +2

Adobe

Software/Design

Adobe spent $20 billion trying to acquire Figma in 2022 - the price of admitting that building browser-native design tools would cost more than buying...

sp500, nasdaq100

AMD (Advanced Micro Devices)

Semiconductors

AMD's stock was at $3 in 2014, its CPU architecture was failing, and extinction seemed inevitable. CEO Lisa Su made the ultimate company-betting decis...

sp500, nasdaq100

Amgen

Biotechnology

Amgen's $33.4 billion revenue in 2024 surged 19% year-over-year, driven primarily by the $27.8 billion Horizon Therapeutics acquisition. The deal adde...

sp500, nasdaq100

Applied Materials

Semiconductor Equipment

Applied Materials ships the machines that make the chips—$27.2 billion in equipment revenue for 2024, representing 73% from semiconductor systems. Thi...

sp500, nasdaq100

ARM Holdings

Semiconductor IP/Technology Licensing

ARM Holdings designs the processor architecture used in 95% of smartphones, nearly all tablets, and billions of embedded devices. The company doesn't...

nasdaq100

Atlassian

Collaboration Software

Atlassian provides collaboration software including Jira and Confluence. Platform economics create network effects within organizations with viral dis...

nasdaq100

Autodesk

Design Software

Autodesk provides design software including AutoCAD and Revit. First-mover advantage in CAD with network effects through file format standards.

nasdaq100

BigCommerce

E-commerce

E-commerce platform BigCommerce provides substrate like coral reef - merchants build stores on infrastructure, creating ecosystem where BigCommerce ex...

nasdaq100

Block

Financial Technology

Block operates Square payment processing and Cash App peer-to-peer payments. Two-sided network effects with platform economics enabling cross-selling.

nasdaq100

Booking Holdings

Online Travel

Booking Holdings operates online travel platforms including Booking.com and Priceline. Two-sided network effects where more properties attract more tr...

nasdaq100

Box

Cloud Storage

Cloud storage Box competes through enterprise lock-in - workflow integrations act like parasitic roots, making extraction costly once embedded in IT i...

nasdaq100

Broadcom

Semiconductors & Infrastructure Software

Broadcom's market capitalization crossed $1.5 trillion in late 2025—the biological equivalent of a blue whale achieving dominance through strategic ho...

sp500, nasdaq100

Cadence Design Systems

Electronic Design Automation

EDA software simulating chip designs before fabrication—testing billions of transistor interactions virtually. Prevents silicon failures like termites...

sp500, nasdaq100

Cisco

Technology / Networking

Cisco closed fiscal 2025 with $56.7 billion in revenue and a remarkable milestone: over 54% now comes from software and recurring subscriptions, up fr...

sp500, nasdaq100

Cloudflare

Internet Infrastructure & Security

Cloudflare provides CDN, security, and edge computing services. Network effects where each new customer improves performance for all users with econom...

nasdaq100

Confluent

Data Streaming

Confluent commercializes Kafka - event streaming that moves data between systems in real-time through distributed queues. Like mycorrhizal networks sh...

nasdaq100

CrowdStrike

Cybersecurity

The July 2024 global outage—8.5 million Windows machines crashing simultaneously, $10 billion in customer losses—should have destroyed CrowdStrike. In...

nasdaq100

Datadog

Cloud Monitoring & Analytics

Observability as sensory nervous system: Datadog's $3.3 billion 2025 revenue (28% year-over-year growth) comes from selling enterprises their own prop...

nasdaq100

DocuSign

Digital Transaction Management

DocuSign provides electronic signature and digital transaction management. First-mover advantage in e-signature with network effects where each signed...

nasdaq100

Dropbox

Cloud Storage

Scatters file fragments across data centers like squirrels cache nuts—redundant storage in multiple locations, reconstruction possible even when indiv...

nasdaq100

Dynatrace

Observability

Distributed sensors monitor application health across cloud infrastructure—octopus-like nervous system for software, detecting performance anomalies a...

nasdaq100

Elastic

Search and Analytics

Search and analytics engine built on Elasticsearch—distributed data indexing like cataloging library shelves. Open source core with commercial extensi...

nasdaq100

Electronic Arts

Video Games

EA develops interactive entertainment including FIFA and Madden. Economies of scale in game development with network effects in multiplayer games.

nasdaq100

Fastly

Cloud Infrastructure

Edge computing network caching content at geographic perimeters, reducing latency by storing copies near users like muscle cells stockpiling ATP for i...

nasdaq100

Fortinet

Cybersecurity

Vertical integration through custom silicon: Fortinet's proprietary ASICs deliver 5-10x better firewall performance than competitors while reducing po...

nasdaq100

Kraft Heinz

Packaged Foods

Kraft Heinz generated $25.8 billion revenue in 2024, down 3% with organic sales declining 2.1% as consumers shifted away from processed foods toward f...

nasdaq100

Lululemon

Athletic Apparel

Lululemon creates premium athletic apparel through vertical integration and community building. Mutualistic networks with ambassadors and resource par...

nasdaq100

Meta

Technology / Social Media

Meta exemplifies both the power and peril of thermal regulation at scale. Q3 2025 revenue hit $51.24 billion (up 26% year-over-year), demonstrating th...

sp500, nasdaq100

Micron Technology

Semiconductors

Micron's $13.6 billion quarterly revenue in Q1 2026 (up 57% year-over-year) reveals what happens when commodity markets hit genuine scarcity. DRAM pri...

sp500, nasdaq100

Mondelez International

Packaged Foods & Snacks

Mondelez International generated $36.4 billion revenue in 2024, up 1.2% with 4.3% organic growth across brands including Oreo, Cadbury, Milka, and Tob...

nasdaq100

MongoDB

Database Software

MongoDB provides document-oriented database platform with flexible schemas. First-mover advantage in NoSQL databases with strong developer network eff...

nasdaq100

Monster Beverage

Beverages

Monster Beverage capitalized on energy drink growth through Coca-Cola distribution partnership. Convergent evolution with Red Bull and mutualistic net...

nasdaq100

Okta

Identity Management

Okta provides identity and access management with first-mover advantage in cloud-native identity. Platform economics through integration network.

nasdaq100

Palo Alto Networks

Cybersecurity

Platform consolidation as predatory strategy: Palo Alto Networks roiled cybersecurity markets in 2024 by offering customers deferred payments to aband...

nasdaq100

Qualcomm

Semiconductors

When mobile phones consumed too much power for x86 chips, Qualcomm's ARM-based processors filled an ecological niche Intel couldn't occupy. This is ad...

sp500, nasdaq100

Roblox

Gaming Platform

Roblox operates gaming platform with multi-sided network effects. More players attract more developers in exponential feedback loops with platform eco...

nasdaq100

Roku

Streaming Platform

Roku provides streaming platform with two-sided network effects. Platform economics create high-margin advertising with first-mover advantage.

nasdaq100

ServiceNow

Enterprise Software

Market dominance through ecosystem entanglement: ServiceNow's 44.4% market share in IT service management isn't defended through product superiority a...

sp500, nasdaq100

Synopsys

Electronic Design Automation

Synopsys doesn't manufacture chips—it creates the software that makes chip design possible. The company holds 38% of the $15 billion electronic design...

nasdaq100

Ulta Beauty

Beauty Retail

Ulta Beauty's 2024-2025 performance demonstrates resource partitioning mastery—occupying the niche between Sephora's prestige-only model and mass reta...

nasdaq100

VeriSign

Internet Infrastructure

VeriSign operates .com and .net domain registry with monopoly position. Extreme first-mover advantage with network effects from established standards.

nasdaq100

Volvo

Commercial Vehicles & Equipment

Volvo Group's 2024 results—SEK 526.8 billion revenue with 12.5% adjusted operating margin and SEK 85.9 billion net cash—fund a phase transition most i...

sp500, nasdaq100

Workday

Technology/Enterprise Software

The cloud HR company that turned a 7-year head start into a $70 billion business - then watched competitors converge on the same solution anyway. Fou...

nasdaq100

Worldpay

Financial Technology

Payment processing and merchant services provider (part of FIS) handling card transactions, alternative payments, and omnichannel commerce solutions f...

sp500, nasdaq100

Zscaler

Cloud Security

Zscaler operates cloud-native security platform for zero trust architecture. First-mover advantage in cloud security with network effects strengthenin...

nasdaq100