Cell Biology

Mitochondria

Membrane-bound organelles in eukaryotic cells that generate most of the cell's ATP through cellular respiration. Often called the 'powerhouses' of the cell.

Used in the Books

This term appears in 8 chapters:

Foundations Metabolism and Burn Rate

"... when you need energy immediately and don't have time for the slower, more efficient pathways. The Krebs Cycle (or citric acid cycle) happens in mitochondria. It takes the pyruvate from glycolysis and completely oxidizes it, harvesting high-energy electrons. This is more efficient than glycolysis alone. *..."

Foundations Reproduction and Replication

"They're symbionts - species that form mutually beneficial partnerships, trading capabilities neither could provide alone. Mitochondria power eukaryotic cells because an ancient bacterium merged with a host cell, creating a symbiotic relationship so successful it's now universal in co..."

Foundations Symbiosis and Exchange

"... mutual advantage. Biology discovered this principle long before business schools did. No complex organism survives in isolation. Your cells contain mitochondria - once independent bacteria that merged with ancestral cells between 1.5 and 2 billion years ago. Every breath you take depends on this ancient symbi..."

Resource Dynamics Caloric Restriction

"Autophagy (Cellular Cleanup)** Inside a well-fed cell, the scene is pure abundance. Ribosomes churn out fresh proteins. Mitochondria bud and multiply. The cell builds, builds, builds - anabolism in overdrive. Damaged proteins accumulate in corners, but who cares? New production out..."

Resource Dynamics Temperature Regulation

"white fat: - White fat: Stores energy (1 gram = 9 calories storage) - Brown fat: Burns energy (1 gram = 300 mitochondria generating heat) - Efficiency: Brown fat generates 300× more heat than white fat - Distribution: Newborns 5% body weight brown fat, adults 0.1% Th..."

And 3 more chapters...

Biological Context

Mitochondria were once free-living bacteria that became permanent symbionts within ancestral eukaryotic cells (endosymbiosis). They retain their own DNA and reproduce independently within cells. Mitochondrial function affects aging, disease, and metabolic capacity.

Related Terms

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cell-biologyenergyfundamental