Biochemistry
Guanine
One of the four nucleotide bases in DNA and RNA, abbreviated as 'G'. Guanine pairs with cytosine through three hydrogen bonds. Also found in guanosine triphosphate (GTP), used in protein synthesis and cell signaling.
Biological Context
G-C rich regions of DNA are more stable due to the three hydrogen bonds per pair. Guanine can form unusual four-stranded structures (G-quadruplexes) at chromosome ends (telomeres) and in gene regulatory regions, affecting DNA replication and gene expression.
Business Application
High G-C content regions are more stable but harder to process. Similarly, some organizational structures are very stable but resistant to change. Knowing where your 'G-C rich regions' are helps identify both strengths (stability) and challenges (rigidity).