Biochemistry

Gluconeogenesis

The metabolic pathway that synthesizes glucose from non-carbohydrate sources like amino acids, lactate, and glycerol. How the body makes glucose when dietary sources are unavailable.

Biological Context

Gluconeogenesis occurs primarily in the liver and kidneys. It's essentially glycolysis in reverse, though with different enzymes at key steps. The process is energy-expensive but essential for maintaining blood glucose during fasting. Proteins (muscle) can be sacrificed to make glucose.

Business Application

Business gluconeogenesis: generating cash from non-revenue sources—selling assets, calling in debts, liquidating inventory. An emergency measure that consumes organizational 'muscle' to maintain essential functions.

Related Terms

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biochemistrymetabolismenergy