Cell Biology
Contact Inhibition
The phenomenon where normal cells stop dividing when they contact neighboring cells. A crucial mechanism preventing uncontrolled growth.
Biological Context
When cells touch each other, signaling pathways trigger cell cycle arrest. This prevents overcrowding and maintains tissue architecture. Cancer cells typically lose contact inhibition, continuing to divide and pile up even when surrounded by other cells.
Business Application
Market contact inhibition: healthy companies slow expansion when they encounter established competitors. Companies that ignore market 'contact inhibition' often trigger destructive price wars or overextend into unprofitable territory.