Chromosome
A structure of tightly coiled DNA and proteins that carries genetic information. Humans have 46 chromosomes (23 pairs); the number varies widely across species.
Used in the Books
This term appears in 8 chapters:
"...ves its normal life - S: DNA replication - the cell copies all its genetic material - G2: More growth, preparation for division - M: Mitosis proper - chromosomes separate, cell divides At multiple points in this cycle, there are checkpoints. Quality control. Is the DNA damaged? Fix it or stop the cycle."
"...alf - a process called mitosis that transforms one cell into two identical daughter cells. Here's what actually happens: The cell duplicates all its chromosomes (the instruction manuals), organizes them into neat pairs, then literally tears itself in two. The entire cell cycle - from one cell to two daughter ..."
"...oduction and Replication When Growth Means Copying What Works Right now, in your gut, a bacterium is dividing. It takes 20 minutes. The circular chromosome - a loop of DNA containing everything needed to build and operate this single cell - duplicates. Enzymes unzip the double helix."
"Recombination**: Sexual reproduction shuffles existing genetic variants through meiotic recombination (crossover between homologous chromosomes). While not creating new mutations, recombination generates new combinations, increasing variation. Recombination rates are also evolvable - some org..."
"Despite its simplicity, it captures the essential dynamics of random sampling in evolution. Consider a diploid (organisms with two copies of each chromosome, like humans) population of size N containing two alleles (versions of a gene) at a locus (a specific position in the genome): A and a."
And 3 more chapters...
Biological Context
Chromosomes ensure genetic material is accurately distributed during cell division. They contain genes arranged in linear order. Chromosome abnormalities—extra copies, missing pieces, rearrangements—can cause developmental disorders and diseases.
Business Application
Organizational chromosomes: the core documents that carry institutional DNA—founding documents, strategic plans, cultural codes. Like biological chromosomes, these must be faithfully copied and distributed as the organization grows and divides.