Genetics

Chromatin

The complex of DNA and proteins (mainly histones) that makes up chromosomes. How DNA is packaged inside the cell nucleus.

Biological Context

Chromatin structure affects gene accessibility. Tightly packed (heterochromatin) regions are typically silent; loosely packed (euchromatin) regions can be transcribed. Chromatin remodeling is a major mechanism of gene regulation. During cell division, chromatin condenses into visible chromosomes.

Business Application

Organizational chromatin: how information and capabilities are packaged and stored. Tightly 'packed' information is harder to access; organizational structure determines what knowledge is readily available versus archived.

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geneticsstructureregulation