Catabolism
The set of metabolic pathways that break down molecules into smaller units, releasing energy. The opposite of anabolism (building up). Catabolism converts complex molecules into simpler ones.
Used in the Books
This term appears in 2 chapters:
"...anufactures the proteins it needs to function, that's anabolism. All of these processes require energy - you have to spend energy to build things. Catabolism is breaking down. It's degradation, deconstruction, harvesting. When your body breaks down fat stores during a fast, that's catabolism."
"... lipids into fatty acids, everything into molecular building blocks. These recycled components get reused. The cell cannibalizes itself to survive - catabolism replacing anabolism. The molecular trigger is elegant. Nutrient sensors detect energy scarcity. AMPK (activated by low ATP) phosphorylates ULK1, whi..."
Biological Context
Catabolic processes include breaking down glucose for energy, digesting food into absorbable nutrients, and breaking down muscle protein during starvation. Catabolism releases energy stored in chemical bonds, powering cellular activities.
Business Application
Corporate catabolism: cutting costs, layoffs, divesting business units, simplifying product lines. During downturns, companies enter catabolic mode—breaking down organizational structure to release resources for survival. Prolonged catabolism depletes capabilities needed for future growth.