Biology of Business

M

75 companies

Microsoft

Software & Cloud Computing

Microsoft's transformation under Satya Nadella represents one of the most successful metabolic pathway shifts in business history. By 2014, the compan...

9 mentions sp500, nasdaq100

Marvel Entertainment

Entertainment & Media

Marvel filed Chapter 11 bankruptcy in December 1996 with $700 million in debt after the comic book market collapsed. Investor Ike Perlmutter provided...

4 mentions

McDonald's

Quick Service Restaurants

McDonald's represents the most successful example of asexual reproduction in business history. When Ray Kroc encountered the McDonald brothers' San Be...

4 mentions sp500

Maersk Line

Shipping & Logistics

The world's largest container shipping company, headquartered in Denmark with 17% global market share and 700+ vessels. Maersk demonstrates fractal lo...

1 mention

Mercado Libre

E-commerce / Fintech

Mercado Libre ('Free Market'), founded by Marcos Galperin in 1999, became Latin America's e-commerce leader by solving the region's fundamental trust...

1 mention

Meta/Facebook

Technology/Social Media

Social media and technology company that demonstrates effective decomposition through open-sourcing. When Facebook reduced internal usage of React Nat...

1 mention

Microsoft Japan

Technology

Japanese subsidiary of Microsoft that conducted a landmark 4-day workweek experiment in August 2019. By closing offices every Friday and implementing...

1 mention

Mitsubishi Motors

Automotive

Japanese automaker added to the Renault-Nissan Alliance in 2016, transforming the two-party coalition into a three-party structure. The addition was i...

1 mention

Moderna

Biotechnology / Pharmaceuticals

Moderna spent 10 years and $2.5 billion with zero revenue. No mRNA drug had ever been approved when they started in 2010. The allocation was extreme:...

1 mention

Mondragon Corporation

Worker Cooperative/Manufacturing

Mondragon is the world's largest worker-owned cooperative - 80,000+ worker-owners, €11.2 billion annual revenue, founded in Spain's Basque Country in...

1 mention

Movie Gallery

Video Rental

Movie Gallery is mentioned as one of Blockbuster's traditional competitors. Blockbuster's selective membrane served them well defending against tradit...

1 mention

Macquarie Group

Financial Services

Macquarie Group's $61 billion market cap demonstrates opportunistic resource allocation across infrastructure, commodities, asset management, and capi...

asx200

Mahindra & Mahindra Limited

Automotive & Conglomerate

Mahindra & Mahindra closed FY25 with ₹1.59 trillion revenue (14% YoY growth) and ₹12,929 crore PAT, demonstrating adaptive radiation across adjacent n...

nifty50

Mailchimp

Marketing Technology

Mailchimp spent 21 years as the textbook ectotherm—profitable from day one, growing without external funding, metabolic rate coupled to market tempera...

MakerDAO

Cryptocurrency / DeFi

In August 2024, MakerDAO rebranded to "Sky," introducing the USDS stablecoin and SKY governance token while keeping original DAI and MKR tokens in cir...

Mallinckrodt

Pharmaceutical

Mallinckrodt's two bankruptcies (2020, 2023) demonstrated how opioid liability could destroy pharmaceutical companies years after the conduct occurred...

Private

Mallinckrodt Pharmaceuticals

Pharmaceutical

Mallinckrodt's October 2020 bankruptcy was driven by $1.6 billion in opioid litigation settlements. The company manufactured 55% of America's opioid a...

NYSE

Manhattan Associates

Technology

Manhattan Associates develops, sells, deploys, and maintains software solutions designed to manage supply chains, inventory, and omnichannel operation...

russell2000

Manning & Napier

Financial Services

Manning & Napier is an independent investment management firm providing investment strategies and solutions for institutional and private wealth clien...

russell2000

Maple

Food Delivery

Maple, David Chang's premium meal delivery startup, raised $29M before shutting down in 2017. The company discovered that chef-driven quality couldn't...

Defunct

Marathon Petroleum Corporation

Energy

America's largest refining system metabolizes 3 million barrels per day of crude oil across 13 refineries, converting hydrocarbons into transportation...

russell2000

MarketAxess Holdings

Financial Technology

MarketAxess operates an electronic trading platform for fixed-income securities providing market transparency and improved efficiency in the corporate...

russell2000, sp400

Marriott International

Hospitality

Marriott International is the world's largest hotel company with more than 30 brands and 8,000 properties across 139 countries. The company operates a...

russell2000

Mars

Consumer Goods/Pet Food

Global confectionery and pet food company that acquired P&G's pet food brands (Iams, Eukanuba) for $2.9B in 2014 as part of P&G's portfolio pruning st...

private

Maruti Suzuki India

Automobiles

43% passenger vehicle market share with 1.71 million units sold in November 2025—Maruti Suzuki dominates Indian automotive ecosystems through phenotyp...

nifty50, bse sensex

Maserati

Automotive/Luxury

Maserati produced 9,760 units in 2024—a 64% collapse from 27,166 in 2023—making it one of the automotive industry's most catastrophic single-year cont...

Mastercard

Payment Networks / Financial Services

The payment network that learned the most profitable war is one you never finish. Mastercard holds 25-30% of the global payment network market, formi...

Mattress Firm (2018)

Retail - Mattresses

Mattress Firm's 2018 bankruptcy came after aggressive expansion left the company with 3,000+ stores—often multiple stores on the same block competing...

Private

McClatchy

Publishing - Newspapers

McClatchy's 2020 bankruptcy ended 163 years of newspaper publishing, including the Miami Herald and Sacramento Bee. The company had acquired Knight Ri...

Defunct, Defunct independence

McKinsey & Company

Management Consulting

In December 2024, McKinsey agreed to pay $650 million to resolve DOJ investigation into its work advising Purdue Pharma on boosting OxyContin sales—ad...

Medicine Man Technologies

Cannabis

Medicine Man Technologies is a cannabis consulting and products company providing operational and technical consulting services to cannabis cultivator...

russell2000

Medley Management

Financial Services

Medley Management, a business development company manager, collapsed in 2021 after years of related-party transactions enriched insiders while depleti...

Defunct

Medtronic

Medical Devices

Medtronic operates medical devices with first-mover advantage in cardiac pacemakers. Network effects from physician training and vertical integration...

sp500

Meituan

Technology/Food Delivery

Meituan wrapped 2024 with RMB 337.6 billion revenue ($46.2B), commanding 60-70% of China's food delivery market through swarm intelligence at planetar...

hangseng

MercadoLibre

Technology/E-commerce

Latin American e-commerce and fintech company founded in 1999 by Marcos Galperin in Argentina. Started as an eBay-style auction marketplace during the...

Mercedes-Benz

Automotive

In February 2024, Mercedes-Benz reversed its 2021 commitment to sell only electric vehicles by decade's end. Revenue fell 4.5% to €145.6 billion, EBIT...

dax40

Merchants Bancorp

Financial Services

Merchants Bancorp is a diversified bank holding company offering multi-family housing and healthcare facility financing, mortgage warehouse financing,...

russell2000

Merck

Pharmaceuticals

Keytruda has reigned as oncology's apex predator for a decade—the PD-1 inhibitor generated $29.48 billion in 2024, an 18% increase from $25.01 billion...

sp500

Merck KGaA

Pharmaceuticals

Merck KGaA is a leading science and technology company operating in healthcare, life science, and electronics sectors, combining pharmaceutical innova...

dax40

Mercury (Brand)

Automotive

Mercury's 2011 discontinuation ended Ford's intermediate brand after 72 years of increasingly confused positioning. Originally 'the car for young prof...

Defunct

Mervyn's

Retail - Department Store

Mervyn's 2008 liquidation ended a California department store chain after private equity ownership extracted real estate value while loading the compa...

Defunct

Meta

Technology / Social Media

Meta exemplifies both the power and peril of thermal regulation at scale. Q3 2025 revenue hit $51.24 billion (up 26% year-over-year), demonstrating th...

sp500, nasdaq100

Metro AG

Retail

German retail company that purchased 85 of Walmart's German stores for $500M in 2006 when Walmart exited after 9 years of losses.

Metso Corporation

Mining Equipment & Industrial Machinery

Metso's €4.9 billion mining equipment business occupies a specialized niche: providing crushing, grinding, and processing infrastructure that enables...

omx

MF Global

Financial Services

MF Global's 2011 bankruptcy was triggered by bets on European sovereign debt that went wrong, combined with missing $1.6 billion in customer funds. CE...

Defunct

MG Rover

Automotive

MG Rover's 2005 collapse ended mass British car manufacturing. The company had been sold by BMW for £10 in 2000 to a consortium that extracted cash wh...

Defunct

MGIC Investment Corporation

Insurance

MGIC Investment Corporation is the holding company for Mortgage Guaranty Insurance Corporation, the nation's leading provider of private mortgage insu...

russell2000

Micron Technology

Semiconductors

Micron's $13.6 billion quarterly revenue in Q1 2026 (up 57% year-over-year) reveals what happens when commodity markets hit genuine scarcity. DRAM pri...

sp500, nasdaq100

Microsoft Azure

Cloud Computing

Microsoft's cloud computing platform, launched in 2010 as a follower to AWS. Azure demonstrates successful late-entrant strategy, growing to approxima...

Midea Group

Home Appliances

Midea Group is one of the world's largest home appliance manufacturers, producing air conditioners, refrigerators, washing machines, and owning brands...

csi300, sse50

Midway Airlines (2003)

Aviation

Midway Airlines' 2003 closure was the second death for an airline name that had failed in 1991. The 2001 revival attempted to serve Chicago's Midway A...

Defunct

Miro

Software

Miro provides collaborative whiteboard platform for distributed teams. Network effects through viral adoption with exponential growth.

private

Mistral AI

Artificial Intelligence

Mistral AI doubled its valuation from €5.8 billion (June 2024) to €11.7 billion (September 2025) via €1.7 billion Series C led by ASML. Revenue climbe...

private

Mitsubishi Corporation

Diversified Trading & Investment

Mitsubishi Corporation functions as Japan's largest sogo shosha (general trading house) - a trophic intermediary connecting resource extraction to man...

nikkei225, topix

Modell's Sporting Goods

Retail - Sporting Goods

Modell's March 2020 bankruptcy ended 131 years of family ownership. The Northeast sporting goods chain faced competition from both Dick's Sporting Goo...

Defunct

Molson Coors Beverage Company

Brewing

When Molson Coors reported $11.6 billion in 2024 revenue—down slightly from the prior year—the 200-year-old brewer faced what biologists call a resour...

Monarch Airlines

Airlines

Monarch Airlines' 2017 collapse stranded 110,000 passengers in the UK's largest peacetime repatriation. The 49-year-old airline couldn't compete with...

Defunct

monday.com

Software - Collaboration

Monday.com functions as a genetic toolkit enabling organizations to construct custom workflow organisms—the company's Work OS platform reached $1 bill...

russell2000

Mondelez International

Packaged Foods & Snacks

Mondelez International generated $36.4 billion revenue in 2024, up 1.2% with 4.3% organic growth across brands including Oreo, Cadbury, Milka, and Tob...

nasdaq100

MongoDB

Database Software

MongoDB provides document-oriented database platform with flexible schemas. First-mover advantage in NoSQL databases with strong developer network eff...

nasdaq100

Monster Beverage

Beverages

Monster Beverage capitalized on energy drink growth through Coca-Cola distribution partnership. Convergent evolution with Red Bull and mutualistic net...

nasdaq100

Montgomery Ward

Retail

Montgomery Ward's 2001 liquidation ended a 128-year retail history. The company that pioneered mail-order catalogs and helped settle the American West...

Defunct

Monzo

Financial Services/Digital Banking

UK digital bank that demonstrated chemical signal alignment during a 2019 PIN security breach. When customer PINs were inadvertently logged in plainte...

Moonpig Group

Retail

Moonpig is the UK's leading online greeting cards and gifting platform. The company allows customers to personalize cards and send gifts with next-day...

ftse250

Morgan Stanley

Investment Banking

September 21, 2008: Morgan Stanley's stock drops 24% in a single day. Credit default swaps - insurance against the bank's collapse - spike to crisis l...

sp500

Motorola Mobility

Consumer Electronics

Motorola Mobility's 2012 acquisition by Google for $12.5 billion, then 2014 sale to Lenovo for $2.9 billion, demonstrated how quickly phone market val...

Sold at loss, Defunct

MoviePass

Entertainment Subscription

MoviePass's 2019 collapse demonstrated that subsidized unit economics can create rapid growth that accelerates death rather than preventing it. The co...

Defunct

Mowi ASA

Food & Beverage

Controlling 20-29% of global Atlantic salmon harvest means engineering aquatic ecosystems at industrial scale. Mowi produced 502,000 tons of salmon in...

oslo

Mt. Gox

Cryptocurrency

Mt. Gox's 2014 collapse after losing 850,000 Bitcoin demonstrates how single points of failure can destroy entire market ecosystems. The exchange hand...

Defunct

MTN Group

Telecommunications

MTN Group crossed 300 million subscribers in Q3 2025—a milestone that understates the biological transformation underway. The company isn't just selli...

jsetop40

Muddy Waters Research

Financial Research

Investment research firm founded by Carson Block that exposed Luckin Coffee's fraud through intensive verification methods including surveillance foot...

MUJI USA

Retail

MUJI USA's July 2020 bankruptcy collapsed the American arm of Japan's minimalist retailer. The company had expanded to 19 U.S. stores targeting urban...

Defunct

Munchery

Food Delivery

Munchery's 2019 sudden shutdown—employees learned via text—demonstrates how food delivery faces death spirals. The prepared meal delivery company had...

Defunct

Munich Re

Reinsurance

For the fourth consecutive year, this €60.8 billion reinsurance organism exceeded profit targets, posting €5.7 billion in 2024 net income (above the €...

dax40

Myspace

Social Media

Myspace's decline from $580 million (2005) to $35 million sale (2011) exemplifies how network effects can reverse. In 2006, Myspace was the world's mo...

Defunct