Citation

Evolution in Mendelian Populations

Sewall Wright

Genetics (1931)

TL;DR

Introduced the island model of population structure

This foundational paper introduced the island model of population structure, establishing the mathematical framework for understanding gene flow. Wright demonstrated that when Nm ≈ 1 (one successful migrant per generation), gene flow is sufficient to counteract genetic drift in moderate-sized populations.

This threshold is remarkably low - 99% of reproduction can be local, but 1% migration overpowers drift. For organizations, this means even small amounts of talent migration or idea exchange can homogenize practices across an industry, preventing differentiation.

Key Findings from Wright (1931)

  • Introduced the island model of population structure
  • Established Nm ≈ 1 threshold: one migrant per generation prevents genetic divergence
  • Migration homogenizes allele frequencies between connected populations
  • Gene flow and drift reach equilibrium based on relative strengths
  • Random sampling in finite populations causes allele frequency changes independent of selection
  • Effective population size determines the strength of drift relative to selection
  • Variance in allele frequency scales inversely with population size

Used in 2 chapters

See how this research informs the book's frameworks:

Related Mechanisms for Evolution in Mendelian Populations

Related Frameworks for Evolution in Mendelian Populations

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