Biology of Business

Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male's odour

Sarah A. Roberts, Deborah M. Simpson, Stuart D. Armstrong, Amanda J. Davidson, Duncan H. Robertson, Lynn McLean, Robert J. Beynon, Jane L. Hurst

BMC Biology (2010)

TL;DR

Named after Mr. Darcy, darcin is the molecular mechanism for 'love at first sight'—one protein creates both instant attraction and individual-specific loyalty.

By Alex Denne

Discovery of a mammalian pheromone that triggers both inherent sexual attraction AND learned preference for a specific individual's odor—explaining how initial contact can create lasting individual-specific loyalty.

Key Findings from Roberts et al. (2010)

  • Darcin (MUP20) is male-specific and triggers inherent female attraction as strong as intact male urine
  • Contact with darcin conditions females to prefer that specific male's airborne odor for 4+ weeks
  • The protein is involatile (must be contacted) while the learned scent is airborne—two-stage system
  • Darcin constitutes ~15% of urinary protein in some strains, <0.5% in others
  • Also stimulates hippocampal neurogenesis in exposed females

Related Mechanisms for Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male's odour

Related Organisms for Darcin: a male pheromone that stimulates female memory and sexual attraction to an individual male's odour

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