Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation

Wilder Penfield, Edwin Boldrey

Brain (1937)

TL;DR

Motor cortex has topographic organization (motor homunculus)

Classic study establishing the motor homunculus - the topographic organization of motor cortex where adjacent brain regions control adjacent body parts. Foundational evidence for centralized motor control architecture in vertebrates.

Key Findings from Penfield & Boldrey (1937)

  • Motor cortex has topographic organization (motor homunculus)
  • Electrical stimulation produces specific motor responses
  • Damage to motor cortex causes corresponding paralysis
  • Central command structure controls voluntary movement

Related Mechanisms for Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation