Citation
Long-term Caloric Restriction Studies in Rhesus Monkeys
TL;DR
30% increase in median survival with caloric restriction
These 30+ year studies provide the strongest evidence that caloric restriction benefits extend to primates - and potentially humans. The Wisconsin study showed dramatic health and survival benefits; the NIA study was more nuanced. Together they demonstrate that while implementation details matter, caloric restriction fundamentally works in primates.
For business applications, these studies validate the core thesis: restriction mechanisms are conserved across species and timescales. What works for worms works for monkeys, suggesting the principles translate to organizational contexts.
Key Findings from Aging & Wisconsin (2009)
- 30% increase in median survival with caloric restriction
- Reduced age-related diseases (diabetes, cancer, cardiovascular)
- Wisconsin study showed clearer benefits than NIA study
- Implementation details (diet composition, timing) matter