Citation
The role of the funny current in pacemaker activity
TL;DR
Funny current (If) underlies spontaneous pacemaker depolarization
Key research on the ionic mechanisms underlying cardiac pacemaker cell automaticity - the fundamental biological basis for distributed cardiac rhythm control that operates without central nervous system input.
Key Findings from DiFrancesco (2010)
- Funny current (If) underlies spontaneous pacemaker depolarization
- Pacemaker cells generate rhythm autonomously
- Distributed pacemaker network provides redundancy